The binding of cocaine to cyclodextrins.
نویسندگان
چکیده
Cocaine binds into beta-cyclodextrin, but not detectably into alpha- or gamma-cyclodextrin, in water solution. NMR studies indicate the geometry of the complex, which is confirmed by molecular mechanics calculations and binding studies on cocaine analogues and cyclodextrin dimers.
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ورودعنوان ژورنال:
- Bioorganic & medicinal chemistry letters
دوره 10 17 شماره
صفحات -
تاریخ انتشار 2000